A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a ...

The fdhF gene encoding the 80-kDa selenopolypeptide subunit of formate dehydrogenase H from Escherichia coli contains an in-frame TGA codon at amino acid position 140, which encodes selenocysteine. We ...

Discover the unique genetic code of Euplotes crassus, where a single codon can represent two amino acids, challenging universal genetics. Living things, from bacteria to humans, depend on a workforce ...

Selenium is an essential trace element that is cotranslationally incorporated into selenoproteins as selenocysteine, the 21st amino acid. Selenocysteine insertion poses a challenge to the cell, ...

The essential balance of redox reactions, protein synthesis and folding, protection of cell membranes, and integrity of genomic DNA depends on a handful of proteins called selenoproteins that include ...

The genetics of a marine protozoan may overturn one of the long-held tenets of protein synthesis. According to conventional wisdom, the genetic code is unambiguous: each DNA triplet, or codon, ...

Expression of the murine leukemia virus pol gene occurs by translational read through of an in-frame UAG codon between the gag and pol coding regions. In a previous study, we mutated the UAG codon to ...

A team led by researchers from Charité – Universitätsmedizin Berlin has succeeded in deciphering a fundamental process of molecular biology: the incorporation of selenocysteine – the ‘21st amino acid’ ...

Nuclear-encoded regulatory proteins control mitochondrial translation. A few, however, are encoded by the mitochondrial DNA (mtDNA) and are produced by the mitochondrial translation machinery.

Living things, from bacteria to humans, depend on a workforce of proteins to carry out essential tasks within their cells. Proteins are chains of amino acids that are strung together according to ...