Scientists have created a new technique that can assess how mutations in the genome influence the packaging of DNA in cells. The genome is massive, and has to be carefully wrapped around proteins so ...

Although previously thought to be neutral, research in yeast suggests that synonymous point mutations may have strongly nonneutral effects. A group of researchers from the University of Michigan (MI, ...

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

A new study reveals 42 hereditary genes which predispose individuals to a higher number of mutations that correlate with a greater probability of developing cancer. A study of 11,000 cancer patients ...

This produces point mutations in the DNA, which are mostly harmless but can sometimes lead to genetic disorders. In the new study, the Surrey researchers discovered that some of these modifications ...

A new long-read sequencing technique has helped researchers investigate how DNA mutations arise in a variety of contexts. A collaboration of researchers led by NYU Langone Health and NYU Grossman ...

Epidermal growth factor receptor (EGFR) is a protein on the surface of your cells that helps them grow. When the gene that codes for EGFR has a mutation, it affects the way this protein works, causing ...