HLA-region genes DQB1-, DQA1- and DRB1 are the major loci (IDDM1) in type 1 diabetes (T1D) susceptibility, where several predisposing and protective alleles and haplotypes have been reported. The ...
In genomewide linkage scans for complex diseases involving many loci with small genetic effects, it may be the case that no loci reach conventional statistical significance. A complementary method of ...
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