Researchers released a consensus statement with recommendations to update T cell nomenclature and improve communication ...

Researchers at the Johns Hopkins Kimmel Cancer Center’s Ludwig Center developed a new treatment that selectively targets ...

When killer T cells of our immune system divide, they normally undergo asymmetric cell division (ACD): Each daughter cell ...

Such an advancement would allow for one of the most successful non-chemo cancer treatments to be done both faster and cheaper ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

An expert discusses IL-18-armored CAR T cells for adults with relapsed B-cell leukemia, showing complete remissions with ...

On February 13, Allogene Therapeutics published new long-term follow-up data on cemacabtagene ansegedleucel, showing the investigative allogeneic chimeric antigen receptor (CAR) T-cell therapy ...

In a person living with HIV, proviruses—strands of HIV DNA—are typically integrated into the T cell genome and become a permanent part of the cell's genetic makeup. This integration enables the ...

The immune system provides an integral defense against cancer growth and progression. Activating an anti-tumor immune response relies on several biological steps that can ultimately result in the ...

The immune system is made up of different types of cells, which have different roles in protecting the body from infection. One type of immune cell called a B cell creates antibodies that attack ...

Antigen-driven TCR signaling in the epidermis during CD8+ TRM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal ...

Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets ...