Intermediate filaments (IFs) are critical parts of the structure of cells. They are essential for both normal tissue structure and function. Enabling cells to withstand the stretch and pressure on the ...

(Nanowerk Spotlight) In animal cells, the well known cytoskeletal proteins actin microfilaments and microtubules are accompanied by a third filament system that in humans consist of a family of more ...

Intermediate filaments may function to integrate mechanically the various structures of the cytoplasmic space in a way that is tailored to the differentiated state of the cell. Figure 1: Major ...

Lamins are members of the intermediate filament (IF) superfamily and are classified as type V IFs. However, the structure of lamin genes indicates that they were possibly the evolutionary pregenitors ...

Biologists have found a unique version of a filament-forming protein in human cells that insects lack. Providing structural support and protection against such conditions as blistering, cataracts and ...

Just as the skeleton and muscles move the human body and hold its shape, the cells of the body are stabilized and moved by a cellular skeleton. This cellular skeleton is a dynamic structure, ...

Whether sustained on the field or in the ring, repeated blows to the head result in a distinctive strain of tau filaments in the brain. In the March 20 Nature, researchers led by Sjors Scheres and ...

The symptoms of neurodegenerative diseases like Alzheimer’s, frontotemporal dementia, and chronic traumatic encephalopathy (CTE) are different, but they have one feature in common: the presence of ...