This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Figure 1: The number of human germline microsatellite mutations in relation to standardized allele size. The absence of an allele-span effect is problematic for theories invoking heterozygote ...

Researchers have changed the way to look at DNA. They show that DNA is much more than a linear sequence of building blocks; it has a 3D structure that influences the variation of human genome-wide ...

In a recent study published in the journal Nature Communications, researchers discovered a family with a germline-encoded telomere template sequence mutation (TTAGGT) in telomerase, which results in a ...

A phylogenetic tree of SARS-CoV-2 sequences, built with Nextstrain, displays sequences colored by their clade and organized by collection date. Over time, sequences mutate and diverge, forming new ...

In a recent bioRxiv* preprint study, researchers from the University of Hawaii showed that the S gene of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuously mutating ...

When scientists investigate the spread of an infectious disease, one area they look at is the genetic sequences of the pathogen. But there’s a snag when it comes to the monkeypox virus, which is now ...

The US Centers for Disease Control and Prevention did not meet a goal to quickly ramp up surveillance for possibly dangerous coronavirus mutations, according to numbers from the federal agency. At the ...

Scientists say they have found a pattern of so-called epigenetic 'marks' in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a ...

Although the genetic cause of many diseases have been identified, it’s estimated that as many as 70% of patients with a rare disorder do not know what causes their disease. Millions of people live ...