AI Designs a Novel PROTAC from Scratch: Insilico's generative AI platform, Chemistry42, successfully designed a first-in-class PROTAC targeting PKMYT1 by creating an entirely new inhibitor and its ...
Reducing the time and expense of engineering PROTAC degraders remains a significant challenge in the pharmaceutical industry. A PROTAC is composed of an E3 ligase ligand (E3-L), a protein of interest ...
This article and associated images are based on a poster originally authored by Nur M. Kocaturk, Andreas Holmqvist, Christina Duncan, Jennifer Riley, Steve Baginski, Graham Marsh, Joel Cresser-Brown, ...