EnteroBiotix announces positive Phase 2 TrIuMPH results supporting EBX-102-02 as a potential first-in-class, oral, full-spectrum microbiome therapy for irritable bowel syndrome

Clinically meaningful improvements in global IBS symptom severity observed as early as Week 1 and sustained through Week 7, with EBX-102-02 ...
Business Wire

Seaport Therapeutics Presents New Meta-Analysis Examining Correlations Between Clinical Trial Design Factors and Placebo Response in Major Depressive Disorder Studies

BOSTON--(BUSINESS WIRE)--Seaport Therapeutics (“Seaport” or the “Company”), a clinical-stage biopharmaceutical company that is advancing novel neuropsychiatric medicines with a proven strategy and ...
Ars Technica

In depression treatment trials, placebo effect is growing stronger

Placebos have occupied an increasingly awkward spot in the medical landscape over the last few decades. Even as placebo-controlled trials have become accepted as the gold standard for evidence, we’ve ...
Psychology Today

Psychology Today

Double-blind placebo studies have been called the gold standard for testing medications, especially psychiatric ones. Since the placebo effect is a psychological one, it stands to reason that its ...
Psychology Today

The Trouble With Double-Blind Placebo Studies

Double-blind placebo studies have been called the gold standard for testing medications, especially psychiatric ones. Since the placebo effect is a psychological one, it stands to reason that its ...
ascopubs.org

Maintenance Defactinib Versus Placebo After First-Line Chemotherapy in Patients With Merlin-Stratified Pleural Mesothelioma: COMMAND—A Double-Blind, Randomized, Phase II Study

Hematopoietic Stem-Cell Transplantation Does Not Improve the Poor Outcome of Children With Hypodiploid Acute Lymphoblastic Leukemia: A Report From Children’s Oncology Group Three hundred forty-four ...