New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying ...

A new study links repeated binge drinking to persistent brain inflammation that reshapes mood, fear learning, and relapse ...

In tauopathies, scientists tend to focus on neuronal tau. They track its pathology and blame it for dysfunctional microglia. Now, researchers led by Celeste Karch at Washington University, St. Louis, ...

A sequence of stress signals among specialized clean-up cells in the brain could at last reveal why some immune responses can cause significant nerve degeneration that results in the loss of memory, ...

Neurodegenerative diseases, traditionally viewed as driven by neuronal decline, are increasingly recognized to involve ...

Microglia respond to proteinopathies by changing their shapes and expression profiles in different ways. Here’s one that has been somewhat overlooked: rod-shaped microglia. These long, straight cells ...

A clearance mechanism involving microglia has been known to relieve neurons of toxic protein aggregates such as those associated with Alzheimer’s disease and Parkinson’s disease. Unfortunately, this ...

Research led by the SickKids Research Institute in Toronto and the University of Pennsylvania, has found that immune-related ...

Chinese Medical Journals Publishing House Co., Ltd. Major depressive disorder (MDD) is a mental health condition that negatively affects the mood of a person and causes a loss of interest in ...