MILAN — Is chronic lymphocytic leukemia (CLL) progression primarily driven by genetic mutations or by external cues from the tumor microenvironment? Despite major strides in targeted therapies, CLL ...

Cancer cells don’t exist in isolation – instead, they live within a complex ecosystem that also includes immune cells, stromal cells, the extracellular matrix, blood vessels and many other factors.

Tissue function is shaped by a complex, multilayered molecular landscape, where even subtle disruptions in spatial organization can trigger – or indicate – the onset of disease. “Spatial biology ...