Scientists at City of Hope ®, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer cells ...

Protein surface (left) and ribbon (right) models of integrin αV’s β-propeller domain illustrate the capacity of Cpd_AV2 (yellow) in disrupting the interaction between integrin β5’s βA loop (cyan; ...

Protein evolution occurs slowly via small incremental mutations—usually. However, dramatic changes can happen: for instance, a fragment of one protein getting copied into the middle of another. While ...

A fluorescent probe for visualizing the signaling dynamics in metastatic cancer cells has been developed. A research team at the University of Turku (Finland), led by Johanna Ivaska and James Conway, ...