Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk", may actually play powerful roles in regulating gene expression. Focusing ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Summary: A team of investigators from Dana-Farber Cancer Institute, The Broad Institute of MIT and Harvard, Google, and Columbia University have created an artificial intelligence model that can ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

Origin-recognition complex (ORC) plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports. Subscribe to our newsletter for the ...

This is the first detailed study of how and where ORC subunits regulate epigenetics and gene expression in human cells. “This is the first detailed study of how and where ORC regulates epigenetics and ...