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Retinal organoids and RPE models for retinal gene therapy development

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Potent DNA-recombination method developed for large cargo delivery in gene therapy

Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying ...
Business Wire

Charles River Launches nAAVigation Vector Platform to Accelerate Gene Therapy Programs

WILMINGTON, Mass.--(BUSINESS WIRE)--Charles River Laboratories International, Inc. (NYSE: CRL) today announced the launch of its nAAVigation™ Vector Platform (nAAVigation). Leveraging decades of Adeno ...
Baylor College of Medicine

Adenoviral Vectors

Ad5 vectors are the most commonly used adenovirus vector. Ad5 vectors transduce a wide range of cell types. They utilize the Coxsackie-Adenovirus Receptor (CAR) to enter cells. Transduction efficiency ...
GEN

Gene Delivery AAV Vector Exploits Cell-Penetrating Peptide to Better Reach CNS

Investigators headed by a team at Brigham and Women’s Hospital have developed an adeno-associated virus (AAV) vector that studies show can far more efficiently cross the blood-brain barrier (BBB), in ...
Forbes

Precision In Business: Lessons From Vector Design In Biotechnology

Kristofer Mussar, PhD, is COO of VectorBuilder and MD of VectorBuilder GmbH, leading global operations and innovation in gene delivery. What if business leaders approached strategy the way scientists ...