Trans-splicing is a unique process in gene expression where a short sequence, known as a spliced leader (SL), is added to the 5' end of mRNA molecules. This mechanism is particularly significant in ...

Johns Hopkins researchers have developed a powerful new AI tool called "Splam" that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able to fill such disparate niches because molecular machinery can cut out and ...

What if a cup of coffee could help treat cancer? Researchers at the Texas A&M Health Institute of Biosciences and Technology ...

Schizophrenia is a complex mental health disorder, but scientists are learning more about what can cause it... | Genetics And ...

One idea has been that speckles are splicing factories. The splicing reaction would happen inside the speckle, and then the spliced product would leave. “What people found is that’s not what happens,” ...

In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of ...

Researchers at the Centre for Genomic Regulation (CRG) have created the first blueprint of the human spliceosome, the complex molecular machine that edits genetic messages transcribed from DNA, ...