The European Medicines Agency (EMA) has published a reflection paper regarding the use of extrapolation when developing medicinal products for paediatric use. The main focus of the reflection paper is ...

Specialists define and discuss extrapolation, along with the importance of strong data in specific disease states. This is a video synopsis/summary of a panel discussion involving Ryan Haumschild, ...

The Centers for Medicare and Medicaid Services (CMS) published its final rule regarding the Medicare Advantage (MA) Risk Adjustment Data Validation (RADV) program in early February 2023.[1] Among ...

Researchers at Shanghai Jiao Tong University have made a groundbreaking discovery in the field of Temporal Knowledge Graphs ...

It is well-known that our intuition is not perfect. We are predictably irrational in a huge number of ways in our everyday lives. But what about something a bit more sophisticated? Are there times ...

Sankhyā: The Indian Journal of Statistics, Series A (1961-2002), Vol. 64, No. 3, In Memory of D. Basu, Part 1 (Oct., 2002), pp. 640-652 (13 pages) The m out of n bootstrap, with or without replacement ...

The final guidance explains some principles for developing biosimilars and establishes some rules about extrapolation across indications for various medical conditions. EMA released final guidance on ...

Click here to view the full version of this article. Recently, both insurance and pension regulators in Europe have been moving away from market-consistent valuations of long-dated liabilities. Market ...

One challenge for statisticians and epidemiologists in projecting the future health risks of climate change is how to estimate exposure-response relationships when temperatures are higher than at ...