The patch clamp is a laboratory technique for studying currents in living cells. It is usually carried out by applying a voltage across the cell membrane and measuring the resulting current. An ...

Manual patch clamping requires considerable skill and experience due to the technically challenging setup requirements, and as such, only allows recording of a small sample of cells (approximately ...

Cells send electrical impulses throughout the body, but electrophysiologists struggled to tune into these signals until the patch clamp technique was developed. Although biophysicist Bernard Katz from ...