DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...
A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...
EMBL researchers created SDR-seq, a next-generation tool that decodes both DNA and RNA from the same cell. It finally opens access to non-coding regions, where most disease-associated genetic variants ...
Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...
The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...
A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged DNA and ward off neurological degeneration including that seen in motor ...
Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA ...
While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...
In recent years, the study of epigenetics and its role in disease has increased dramatically. DNA methylation, which influences the ability of proteins to bind the DNA and thereby regulates gene ...