This review highlights how the rotating wall vessel bioreactor has been used to establish physiologically relevant three-dimensional monotypic and co-culture models of human cells and tissues. These ...

Using an ovine model, researchers reconstructed jawbones by filling 3D printed bioreactors with either autologous bone or synthetic graft and implanting the bioreactors for 9 weeks adjacent to sheep ...

Schematic of a typical bioreactor. Key components include the reactor tank, agitation system, feeding pump, thermal jacket, submerged aerator, and sensor probes for monitoring and maintaining optimal ...

Current preclinical models in tumor biology are limited in their ability to recapitulate relevant (patho-) physiological processes, including autophagy. Three-dimensional (3D) growth cultures have ...